Mainoo, who scored in the remarkable 5-4 comeback win over Lyon in the last round, is also an option as a substitute for Amorim.
“Ugarte we played in the last game against Lyon and they combined quite well [in midfield]. We want a bit of stability in this moment, in this game.
“They are a team that want to press really high so we put a team that can cope with that.”
Rasmus Hojlund leads the line after scoring on the south coast and another goal would take him to double figures for the season. The Dane has five strikes to his name in this competition, although all of them came during the league phase.
As Amorim hinted on Wednesday, Amad and Matthijs de Ligt could play a part later in the game as they have been named among the substitutes.
Jonny Evans is not on the bench, as his return from injury is being managed carefully, while the ineligible Sekou Kone and Chido Obi are the other members of the group who haven’t been included in the matchday squad.